insulin resistance

noun

: reduced sensitivity to insulin by the body's insulin-dependent processes (such as glucose uptake and lipolysis) that is typical of type 2 diabetes but often occurs in the absence of diabetes

Examples of insulin resistance in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
This includes a blood pressure check, similar to Apple’s Hypertension notifications, as well as monitoring for insulin resistance. Andrew Gebhart, PC Magazine, 15 Aug. 2026 These include monthly summaries involving blood pressure trends, sleep breathing quality and insulin resistance trends. Kurt Knutsson, FOXNews.com, 15 Aug. 2026 Untreated, high insulin resistance can lead to conditions such as prediabetes and Type 2 diabetes. Bloomberg, Mercury News, 12 Aug. 2026 Key Takeaways Metabolically unhealthy normal weight is often associated with higher visceral fat, fatty liver disease, insulin resistance, and abnormal cholesterol levels. Amy Brownstein, Verywell Health, 7 Aug. 2026 See All Example Sentences for insulin resistance

Word History

First Known Use

1927, in the meaning defined above

Time Traveler
The first known use of insulin resistance was in 1927

Cite this Entry

“Insulin resistance.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/insulin%20resistance. Accessed 20 Aug. 2026.

Medical Definition

insulin resistance

noun
: reduced sensitivity to insulin by the body's insulin-dependent processes (as glucose uptake, lipolysis, and inhibition of glucose production by the liver) that results in decreased activity of these processes or an increase in insulin production or both and that is typical of type 2 diabetes but often occurs in the absence of diabetes
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