insulin resistance

noun

: reduced sensitivity to insulin by the body's insulin-dependent processes (such as glucose uptake and lipolysis) that is typical of type 2 diabetes but often occurs in the absence of diabetes

Examples of insulin resistance in a Sentence

Recent Examples on the Web

This condition is most common in people with metabolic conditions like obesity, insulin resistance, high cholesterol, or high blood pressure.1 MASH can become quite severe. —Health, 12 May 2025

Preventing obesity and insulin resistance could dramatically shift lifetime cancer risk. —Jesse Pines, Forbes.com, 10 May 2025

Blood pressure and cholesterol tend to rise during this time, as does insulin resistance, a condition that can lead to diabetes. —Anna North, Vox, 6 May 2025

Some research even reports that current marijuana users have fasting insulin levels 16% lower and insulin resistance 17% lower than non-users Obesity is a major risk factor for developing type 2 diabetes and for complications in those already diagnosed. —Tribune Content Agency, Mercury News, 22 Apr. 2025

Word History

First Known Use

1927, in the meaning defined above

Rhymes for insulin resistance

• magnetoresistance
• assistance
• consistence
• desistance
• existence
• insistence
• persistence
• subsistence
• coexistence
• nonexistence
• distance

Medical Definition

insulin resistance

noun

: reduced sensitivity to insulin by the body's insulin-dependent processes (as glucose uptake, lipolysis, and inhibition of glucose production by the liver) that results in decreased activity of these processes or an increase in insulin production or both and that is typical of type 2 diabetes but often occurs in the absence of diabetes