insulin resistance

noun

: reduced sensitivity to insulin by the body's insulin-dependent processes (such as glucose uptake and lipolysis) that is typical of type 2 diabetes but often occurs in the absence of diabetes

Examples of insulin resistance in a Sentence

Recent Examples on the Web

Kefir consumption can help regulate blood sugar levels and reduce insulin resistance. — Jillian Kubala, Health, 23 July 2026

Consider asking your primary care physician about fasting glucose testing before your next annual visit; insulin resistance is the modifiable factor the trials keep returning to. — Samantha Agate, Fort Worth Star-Telegram, 22 July 2026

For example, Gjoni says worsening insulin resistance and declining metabolic health can appear in bloodwork years before a diabetes diagnosis. — Helen Carefoot, Flow Space, 14 July 2026

In addition to treating diabetes, metformin can support weight loss, help manage the insulin resistance associated with polyendocrine metabolic ovarian syndrome (PMOS), and may benefit heart health. — Abby Norman, Verywell Health, 6 July 2026

Word History

First Known Use

1927, in the meaning defined above

Rhymes for insulin resistance

• magnetoresistance
• assistance
• consistence
• desistance
• existence
• insistence
• persistence
• subsistence
• coexistence
• nonexistence
• distance

Medical Definition

insulin resistance

noun

: reduced sensitivity to insulin by the body's insulin-dependent processes (as glucose uptake, lipolysis, and inhibition of glucose production by the liver) that results in decreased activity of these processes or an increase in insulin production or both and that is typical of type 2 diabetes but often occurs in the absence of diabetes